An Ethnography of Entanglements: Mercury’s Presence and Absence in Artisanal and Small-scale Gold-mining in Antioquia, Colombia

This paper describes a ‘follow the thing’ methodology as applied to an ethnography of entanglements. This methodology allowed for a materially and politically nuanced understanding of Antioquia, Colombia’s response to mercury pollution. This pollution primarily originates from the Artisanal and Small-Scale Gold Mining (ASGM) industry where mercury is employed in the gold extraction process. In following the mercury, the authors experiment with an ethnography of entanglements. The paper discusses how they address the current lacunae in mining ethnographies by focussing on mining as ‘practice’, going past the provision of technical descriptions of mining and ethnographic descriptions of miners to an ethnography of mining. This ethnographic approach considers the politics of materiality and addresses a lack of attention to the impacts of the presence and absence of materials on social life. Various mining practices in Antioquia illuminate how entanglements between miners and mercury have been co-constitutive of particular modes of ASGM. The paper will also provide examples of ‘negative mercury entanglements’ where efforts have been made to extricate mercury from mining practices. Rather than creating a vacuum, these mercury absences have been generative of new contested symbolic and material arrangements including entrepreneurial and ‘responsible’ mining, debates over miners’ rights, and the creation of new political relationships between ASGM and large-scale mining companies.fals

Hand-held instrument should relieve hematoma pressure

Portable instrument relieves hematomas beneath fingernails and toenails without surgery. This device simplifies the operative procedure with an instant variable heating tip, adjustable depth settings and interchangeable tip sizes for cauterizing small areas and relieving pressurized clots

Evaluating the psychometric properties of the multigroup ethnic identity measure (MEIM) within the United Kingdom

In the present study, we examined the psychometric properties of the Multigroup Ethnic Identity Measure (MEIM) (Phinney, 1992; Phinney & Alipuria, 1990) among an ethnically diverse sample within the United Kingdom. In initial analyses, we evaluated the goodness-of-fit of a one-factor model (i.e., global ethnic identity) and the goodness-of-fit of a two-factor model (i.e., correlated but distinct Exploration and Commitment components). Results of initial confirmatory factor analyses led us to reject both the one-factor and two-factor models. Results of subsequent exploratory and confirmatory factor analyses revealed a three-factor structure (i.e., correlated but distinct Behavioral, Cognitive, and Affective components of ethnic identity) among the sample as a whole (n = 234) and among Asian Indian persons (n = 88) in particular, though resulst were mixed among White U.K./Irish persons (n = 54) in particular. Implications for the study of ethnicity-related concepts in the incerasibgly multi-cultural U.K. are discussed

Satellite retrieval system

A satellite retrieval system with first and second pairs of coacting parallel bars are separately mounted in spaced parallel planes on the front of a spacecraft. The bars of one pair are at right angles to bars of the other pair, and together the two pairs of bars effect a variable aperture adapted to close around a rod extending from a second spacecraft to effect the capture of the latter

Tailored codes for small quantum memories

We demonstrate that small quantum memories, realized via quantum error correction in multi-qubit devices, can benefit substantially by choosing a quantum code that is tailored to the relevant error model of the system. For a biased noise model, with independent bit and phase flips occurring at different rates, we show that a single code greatly outperforms the well-studied Steane code across the full range of parameters of the noise model, including for unbiased noise. In fact, this tailored code performs almost optimally when compared with 10,000 randomly selected stabilizer codes of comparable experimental complexity. Tailored codes can even outperform the Steane code with realistic experimental noise, and without any increase in the experimental complexity, as we demonstrate by comparison in the observed error model in a recent 7-qubit trapped ion experiment.Comment: 6 pages, 2 figures, supplementary material; v2 published versio

William H. Sorrell, Attorney General of Vermont, et al. v. IMS Health Inc., et al. - Amicus Brief in Support of Petitioners

On April 26, 2011, the US Supreme Court will hear oral arguments in the Vermont data mining case, Sorrell v. IMS Health Inc. Respondents claim this is the most important commercial speech case in a decade. Petitioner (the State of Vermont) argues this is the most important medical privacy case since Whalen v. Roe. The is an amicus brief supporting Vermont, written by law professors and submitted on behalf of the New England Journal of Medicin

Inhibition of glucocorticoid-induced apoptosis by targeting splice variants of \u3ci\u3eBIM\u3c/i\u3e mRNA with small interfering RNA and short hairpin RNA.

Glucocorticoids (GCs) induce apoptosis in lymphocytes and are effective agents for the treatment of leukemia. The activated glucocorticoid receptor (GR) initiates a transcriptional program leading to caspase activation and cell death, but the critical signaling intermediates in GC-induced apoptosis remain largely undefined. We have observed that GC induction of the three major protein products of the Bcl-2 relative Bim (BimEL, BimS and BimL) correlates with GC sensitivity in a panel of human pre-B acute lymphoblastic leukemia (ALL) cell lines. To test the hypothesis that Bim facilitates GC-induced apoptosis, we reduced BIM mRNA levels and Bim protein levels by RNA interference (RNAi) in highly GC-sensitive pre-B ALL cells. Reducing Bim proteins by either electroporation of synthetic siRNA duplexes or lentiviral-mediated stable expression of shRNA inhibited activation of caspase-3 and increased cell viability following GC exposure. We also observed that the extent of GC resistance correlated with siRNA silencing potency. siRNA duplexes that reduced only BimEL or BimEL and BimL (but not BimS) exhibited less GC resistance than a potent siRNA that silenced all three major isoforms, implying that induction of all three Bim proteins contributes to cell death. Finally, the modulation of GC-induced apoptosis caused by Bim silencing was independent of Bcl-2 expression levels, negating the hypothesis that the ratio of Bim to Bcl-2 regulates apoptosis. These results offer evidence that induction of Bim by GC is a required event for the complete apoptotic response in pre-B ALL cells